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Thursday, November 12, 2009

Researchers have found a crucial genetic difference between humans and chimps that could help explain our language and speech abilities. The difference lies in a gene called FOXP2 which encodes for a protein of the same name. This acts as a transcription factor, controlling the activity of other genes.

The human and chimp versions of the protein differ in only two of their 740 amino acid components, but when researchers at the University of California, Los Angeles, replaced the human gene with the chimp version in neurons grown in the laboratory, they found it affected the expression of at least 116 other genes.

The results are detailed in a paper published on Thursday in the scientific journal Nature.

Author of the study Dr. Daniel Geschwind, of the David Geffen School of Medicine at UCLA, said the gene had a “major role” in differences between chimps and humans. “We showed that the human and chimp versions of FOXP2 not only look different but function differently too.”

Some of the affected genes control the formation of connections in the brain, whilst others relate to facial movements. Several have already been found to be involved in language disorders. Mutations in FOXP2 itself were also known to affect speech and language; the gene was first identified in members of a family suffering from language problems who were found to share a genetic mutation.

Frances Vargha-Khadem at University College London has studied patients with FOXP2 mutations, and agrees with the new research. As well as language problems, some of her subjects have changes in the shape of their jaws, mouths and tongues. She thinks that chimps may also have these differences.

“We believe FOXP2 is not only important for the higher order cognitive aspect of language but also for the motor aspect of speech and language,” said Genevieve Konopka, one of the authors of the paper at UCLA.

Previous research indicates that the changes in FOXP2 occurred around 200,000 years ago with the rise of modern humans. Geschwind also suggests that several of the related genes may have evolved together. Preliminary studies have shown signs that they too emerged relatively recently.

Scientists are now keen to further study FOXP2 and the genes that it affects. Geschwind believes this could eventually lead to breakthroughs in treatment for disorders such as autism and schizophrenia, which affect language skills.

The study was funded by the National Institute of Mental Health, the A.P. Giannini Foundation and the National Alliance for Research on Schizophrenia and Depression.

Saturday, July 9, 2005

Today The Walt Disney Company issued a joint statement with business partners Roy E. Disney and Stanley Gold to the media, as a show of reunion between the two camps after nearly three years of hostility.

Roy E. Disney, son of company co-founder Roy O. Disney and nephew of the company namesake Walt Disney, had resigned from his job as chairman of Feature Animation at the company after experiencing difficulty with the company’s board of directors, many of whom were biased towards company CEO Michael Eisner‘s view of what direction the company should take.

Eisner is due to retire from the company this September, and the talks with Disney and Gold are believed to have been led by Eisner’s successor, Bob Iger, who is currently President and COO of the company. Iger has shown great interest in building relationships back up with many companies who have refused to work with Disney until Eisner leaves, such as Pixar Animation and George Lucas.

Large scores of Disney fans had hoped Roy would read the Disneyland Dedication Speech on the theme park’s fiftieth birthday next week, which was originally read by Walt on the park’s opening day, but Roy had already entered an annual sailing race from Los Angeles to Honolulu.

Monday, April 30, 2007

Microsoft has finally released its long awaited “Silverlight” into Alpha Testing for the general public. “It’s the biggest challenge for Microsoft right now,” said Brent Thill, an analyst from Citigroup. This is the most direct threat to date, that Microsoft has posed to Adobe (makers of the popular Flash platform).

The creators of Silverlight have been promising a single plug-in which will work across all browsers and operating systems and will offer a rich video and interactive media experience which can be embedded within Web sites.

Microsoft has also promised to make some of the Silverlight technologies open source. This has been a popular decision among the computing industry, and has been a step away from the usual protection of their products.

While at MIX07, Microsoft also discussed its new package called Expression, which is set to be released in June, and will be an alternative to Adobe Creative Suite 3 (CS3).

Wednesday, February 4, 2009

According to the newly formed BNO News Agency, an unnamed man tried to hang himself on an American Airlines flight which took off from Cibao International Airport in the Dominican Republic and was traveling to John F. Kennedy International Airport in New York City located in the state of New York.

American Airlines flight 834 was en-route to New York when the pilot reported that there was a medical emergency on board the plane. BNO says that a man had attempted to hang himself while the plane was in mid-flight. When the plane landed, the man was taken off the plane by emergency services who were on standby at JFK Airport.

Despite the report, American Airlines previously refused to comment on the incident because of the passengers privacy, but an unnamed official said that they had heard about the incident, “but [believed] it is not true.” The airline later stated to BNO that “the passenger did not try to commit suicide, however the passenger did have a medical condition that prompted our crew to call the tower and request assistance.” Even though the airline insists there was no suicide attempt, BNO states that the FBI was called and put on standby at the airport along with emergency services. Their involvement in the situation is not yet known, but BNO says the FBI is investigating.

On February 10, 2006, a man died after hanging himself in a bathroom aboard a United Airlines flight traveling from Washington, D.C. to Los Angeles, California.

Thursday, March 24, 2005

New figures on the Indian Ocean Tsunami disaster death toll have been released by Indonesia‘s National Disaster Relief Coordination Agency. It confirms 126,473 dead and 93,943 missing in Indonesia, the worst hit nation by far.

The tsunami was the result of an undersea earthquake near the northern tip of Sumatra (in Indonesia) on December 26. The waves struck as far away as Tanzania on Africa’s east coast.

According to Sri Lanka’s Centre for National Operations, it was the second hardest-hit by the disaster with 30,957 dead, with another 5,637 people listed as missing.

According to SBS World News today, the total dead and missing for all eleven countries damaged by the tsunami now stands at 282,517.

Over a thousand Europeans were killed in the disaster. Mostly holiday-makers, of those lost it is estimated that one third were German. Another 1,100 were listed as missing.

Tuesday, October 14, 2008

The San Diego, California suburb of Chula Vista has responded to the recent housing crisis with an aggressive blight control ordinance that compels lenders to maintain the appearance of vacant homes. As foreclosures increase both locally and throughout the United States, the one year old ordinance has become a model for other cities overwhelmed by the problem of abandoned homes that decay into neighborhood eyesores.

Chula Vista city code enforcement manager Doug Leeper told the San Diego Union Tribune that over 300 jurisdictions have contacted his office during the past year with inquiries about the city’s tough local ordinance. Coral Springs, Florida, and California towns Stockton, Santee, Riverside County, and Murietta have all modeled recently enacted anti-blight measures after Chula Vista’s. On Wednesday, 8 October, the Escondido City Council also voted to tighten local measures making lenders more accountable for maintenance of empty homes.

Under the Chula Vista ordinance lenders become legally responsible for upkeep as soon as a notice of mortgage default gets filed on a vacant dwelling, before actual ownership of the dwelling returns to the lender. Leeper regards that as “the cutting-edge part of our ordinance”. Chula Vista also requires prompt registration of vacant homes and applies stiff fines as high as US$1000 per day for failure to maintain a property. Since foreclosed properties are subject to frequent resale between mortgage brokers, city officials enforce the fines by sending notices to every name on title documents and placing a lien on the property, which prevents further resale until outstanding fines have been paid. In the year since the ordinance went into effect the city has applied $850,000 in fines and penalties, of which it has collected $200,000 to date. The city has collected an additional $77,000 in registration fees on vacant homes.

Jolie Houston, an attorney in San Jose, believes “Lenders will respond when it costs them less to maintain the property than to ignore local agency requirements.” Traditionally, local governments have resorted to addressing blight problems on abandoned properties with public funds, mowing overgrown lawns and performing other vital functions, then seeking repayment afterward. Chula Vista has moved that responsibility to an upfront obligation upon lenders.

As one of the fastest growing cities in the United States during recent years, Chula Vista saw 22.6% growth between 2000 and 2006, which brought the city’s population from 173,556 in the 2000 census to an estimated 212,756, according to the U.S. Census Bureau. Chula Vista placed among the nation’s 20 fastest growing cities in 2004. A large proportion of local homes were purchased during the recent housing boom using creative financing options that purchasers did not understand were beyond their means. Average home prices in San Diego County declined by 25% in the last year, which is the steepest drop on record. Many homeowners in the region currently owe more than their homes are worth and confront rising balloon payment mortgages that they had expected to afford by refinancing new equity that either vanished or never materialized. In August 2008, Chula Vista’s eastern 91913 zip code had the highest home mortgage default rate in the county with 154 filings and 94 foreclosures, an increase of 154% over one year previously. Regionally, the county saw 1,979 foreclosures in August.

Professionals from the real estate and mortgage industries object to Chula Vista’s response to the crisis for the additional burdens it places on their struggling finances. Said San Diego real estate agent Marc Carpenter, “that kind of measure will add additional costs to banks that have been hit really hard already and ultimately the cost will be transferred down to consumers and investors.” Yet city councils in many communities have been under pressure to do something about increasing numbers of vacant properties. Concentrations of abandoned and neglected homes can attract vandals who hasten the decline of struggling neighborhoods. Jolie Houston explained that city officials “can’t fix the lending problem, but they can try to prevent neighborhoods from becoming blighted.”

CEO Robert Klein of Safeguard, a property management firm, told the Union Tribune that his industry is having difficulty adapting to the rapidly changing local ordinances. “Every day we discover a new ordinance coming out of somewhere”, he complained. Dustin Hobbs, a spokesman from the California Association of Mortgage Bankers agreed that uneven local ordinances are likely to increase the costs of lending. Hobbs advised that local legislation is unnecessary due to California State Senate Bill 1137, which was recently approved to address blight. Yet according to Houston, the statewide measure falls short because it fails to address upkeep needs during the months between the time when foreclosure begins and when the lender takes title.

Wednesday, April 25, 2007

The Iranian police forces have faced criticism from Ayatollah Hashemi Shahrudi, the head of the judiciary who was appointed by Grand Ayatollah Ali Khamenei, for their re-invigorated campaign to do away with un-Islamic dress.

Ayatollah Shahroudi proclaimed, “Tough measures on social problems will backfire and have counter-productive effects.” Others have, of course, made it clear that un-Islamic dress can lead to moral corruption, engender innumerable vices, and hurt the Islamic character of the nation.

Some believe that no one had any issue with the creation of an Islamic atmosphere. The core of the matter revolves around the implementation of the Islamic dress code; additionally, heavy-handed measures should be shunned. For instance, Mehdi Ahmadi, information head of Tehran’s police, told Al Jazeera: “Some citizens may complain about the way the law is being enforced but they all agree with the plan itself.”

According to one student, “You simply can’t tell people what to wear. They don’t understand that use of force only brings hatred towards them, not love.” Nevertheless, Hojatoll-Islam Mostafa Pour-Mohammadi, Iran’s interior minister who is in charge of policing, prognosticated positive feedback from the populace when he said, “People are unhappy with the social and moral status of the society. They expect that the fight against social insecurity be properly implemented.” Thus, Hujjat al-Islam Pour-Mohammadi re-iterated the necessity of proper implementation and methodology towards the restoration of morality in the Islamic Republic. Islamic officials and religious people affirm that this is indispensable to promote righteousness, curb sin, and bring open sinners to justice.

Following the Islamic Revolution in 1979, hijab became mandatory in Iran for every woman including foreigners after over 98% of citizens voted for an Islamic government. Women may face caning up to 74 strokes for failing to observe hejab. In this recent crackdown, the authorities have arrested many citizens throughout the country. Not only have women been taken into custody for their hair being uncovered on their foreheads and tight clothes that show body shapes, For men they need to cover from knee to their waist as according to Sharia Even a foreign journalist was detained because the photograph on her press card was indecent.

It has not been clear whence the directive for the re-newed clampdown emanated. Some have blamed Mahmoud Ahmadinejad while Gholam Hossein Elham, the government spokesman, stated to reporters, “The police work as agents of the judiciary to confront crimes. The government as an executive body does not interfere in the affairs of the judiciary.” The following pre-election speech seems to corroborate this latter statement: